Advanced Liquid And Syrup Manufacturing Plants For The Canadian Pharmaceutical Industry

Advanced Liquid and Syrup Manufacturing Plants for Pharmaceutical Excellence in Canada

In today’s highly regulated and competitive pharmaceutical industry in Canada, efficiency, sterility, and consistency are non-negotiable. When it comes to oral liquid formulations like syrups, suspensions, emulsions, elixirs, and drops, pharmaceutical manufacturers demand cutting-edge technology that guarantees both product safety and regulatory compliance.

At Technogen Enterprise, headquartered in Ahmedabad, India and serving clients across Canada and North America, we specialize in designing, engineering, and supplying world-class liquid and syrup manufacturing plants. With decades of expertise in pharmaceutical machinery, our solutions are trusted worldwide for their durability, scalability, and ability to meet the strictest GMP and FDA standards.

Whether you are a Canadian startup in the pharma sector or a global manufacturer expanding production capacity, our liquid and syrup manufacturing systems are tailored to ensure precision mixing, minimal manual handling, and optimal hygiene—critical factors in oral liquid production.

Why Choose Technogen Liquid & Syrup Manufacturing Plants?

Pharmaceutical production requires more than just machinery—it requires integrated solutions that deliver efficiency and uncompromised quality. Here’s why our liquid plants are trusted across industries:

• ✔ GMP & FDA Compliance: Designed to meet Health Canada, USFDA, and ASME SEC VIII DIV 1 standards.

• ✔ Contact Parts in SS 316L: Guarantees corrosion resistance, product purity, and durability.

• ✔ Flexible Capacities: Ranging from 50 Litres to 20,000 Litres to suit both small and large manufacturers.

• ✔ CIP/SIP Integration: Automated Clean-In-Place and Sterilize-In-Place systems for reduced downtime.

• ✔ Reduced Manual Handling: Automation minimizes contamination risks and ensures operator safety.

• ✔ High Efficiency: Robust agitators, variable-speed drives, and jacketed vessels ensure precise mixing and heating.

Core Components of the Liquid/Syrup Manufacturing Plant

A complete plant includes specialized vessels and support systems, all engineered for seamless production:

• Syrup Manufacturing Vessel (Jacketed): Main unit for syrup formulation with precise mixing and temperature control.

• Sugar Melting Vessel (Jacketed): Dissolves sugar efficiently to create a consistent base syrup.

• Storage Vessel (Non-Jacketed): Maintains finished liquid formulations under sterile conditions.

• Zero Hold Up SS Filter Press: Ensures clarity and purity by removing particulates.

• Inline Sugar Syrup Filter: Provides fine filtration for raw syrup before transfer.

• Transfer Pump (Lobe Pump): Ensures hygienic transfer of liquids between vessels.

• Working Platform: Safe, ergonomic design for operators.

• Standard Control Panel: Centralized automation and monitoring with optional PLC and HMI.

• Optional In-Line Homogenizer: For formulations requiring uniform particle size and enhanced stability.

Technical Excellence in Every Vessel

Syrup Manufacturing Vessel (1000 Litres Example)

• Contact Parts: SS 316

• Design Code: ASME SEC VIII DIV 1

• Agitator: Bottom-mounted propeller with variable speed control

• Mechanical Seal: Double cartridge water-cooled

• CIP/SIP: Fully integrated for sterility

• Pressure Handling: Up to 3 kg/cm² working pressure

Sugar Melting Vessel

• Specifically engineered for rapid sugar dissolution

• Steam jacket for heating and ceramic wool insulation for energy efficiency

• Electronic water electro-sensor for motor safety

Storage Vessel

• Non-jacketed stainless steel tank for safe storage

• Integrated propeller agitator for maintaining suspension homogeneity

• Mirror-finish interior for hygiene compliance

Benefits of Our Design

• Stainless Steel Purity:

  • SS 316L for all contact parts ensures pharmaceutical-grade quality.

  • SS 304 for non-contact components offers strength and cost efficiency.

• Jacketed Vessels:

  • Provide precise temperature control for sensitive ingredients.

  • Accelerate batch times with faster heating/cooling.

• CIP/SIP Integration:

  • Automates cleaning and sterilization.

  • Reduces downtime and manual errors.

  • Guarantees compliance with cGMP standards.

• Zero Hold Up Filter Press:

  • Maximizes yield by minimizing product loss.

  • Provides clarity up to 10–15 microns filtration.

• Agitation Technology:

  • Bottom-mounted propellers ensure complete homogenization.

  • Variable frequency drives provide speed flexibility for different formulations.

Typical Manufacturing Process Flow

1. Sugar Syrup Preparation

   • Sugar and purified water are mixed in the Sugar Melting Vessel.

   • Heated through a jacket for complete dissolution.

   • Pre-filtered using an Inline Sugar Syrup Filter.

2. Formulation in Syrup Manufacturing Vessel

   • Base syrup is transferred into the main vessel.

   • APIs, preservatives, flavors, and excipients are added.

   • Agitators ensure complete mixing, while jackets manage heating/cooling.

   • Optional In-Line Homogenizer ensures fine particle distribution.

3. Final Filtration

   • Product passes through the Zero Hold Up SS Filter Press.

   • Removes micro-impurities, ensuring pharmaceutical clarity.

4. Storage & QC Sampling

   • Filtered syrup is transferred to Storage Vessel(s).

   • Homogeneity maintained until packaging.

   • Batch undergoes quality control tests for purity, pH, and microbial limits.

5. CIP/SIP Cleaning Cycle

   • Automated cleaning and sterilization prepare the system for the next batch.

Applications Across the Canadian Pharma Industry

Our liquid and syrup plants are ideal for:

• Oral Syrups & Solutions – cough syrups, vitamin syrups, elixirs

• Oral Suspensions – antacids, antibiotics, probiotics

• Emulsions – nutraceuticals, pediatric formulations

• Drops & Mixtures – pediatric and geriatric oral dosage liquids

Beyond pharmaceuticals, our technology also supports nutraceuticals, food supplements, and health beverages—all requiring the same level of hygiene and consistency.

Scope of Supply

Supplied by Technogen Enterprise:

• Complete Liquid Manufacturing Plant

• Standard Control Panel

• SS 316 Contact Parts / SS 304 Non-Contact Parts

• Optional: In-Line Homogenizer & Load Cell

Client’s Scope (On-Site Connections):

• Water and steam line connections

• Electrical connections for agitator motors

• Installation of bulbs on vessel fittings

Why Canadian Pharma Companies Trust Technogen

• Decades of Expertise: Trusted globally in pharma machinery manufacturing.

• Regulatory Confidence: Equipment designed to meet Health Canada standards.

• Customization: Flexible capacities and design modifications to suit Canadian operations.

• After-Sales Support: Dedicated support for installation, validation, and operator training.

Partner with Us for Pharmaceutical Excellence

At Technogen Enterprise, we believe that precision engineering drives better healthcare outcomes. Our liquid and syrup manufacturing plants are more than machinery—they are complete solutions built to deliver purity, efficiency, and regulatory compliance.

Whether you are scaling production or setting up a new facility in Canada, our team is ready to partner with you.

Contact us today to discuss your requirements and discover how Technogen Enterprise can elevate your pharmaceutical liquid production.